15 Comments
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HidingIdentityFromFascists's avatar

Excellent information. Thank you!

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Lynne greenwald's avatar

I don’t have a question. I just want to thank you immensely for this clarifying information. I am a subscriber and I send your messages to my family and a group of friends and colleagues. They will all be so grateful for this information. It really does give us not only an understanding of what’s going on in our body but also measures that we can use to monitor and improve.

Lynne 🙏🏻

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Dr. Lucy McBride's avatar

Thank you - and I am so glad!

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Paul K's avatar

Is it possible for too much intensive exercise (e.g., marathon training) to create inflammation that contributes to atherosclerosis?

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Dr. Lucy McBride's avatar

No, exercise is excellent for reducing the risk for atherosclerosis :)

Intensive exercise will transiently increase skeletal (ie mechanical) inflammation due to wear and tear on muscles, joints, and ligaments, but that is a distinctly different kind of inflammation and reflects the natural response to exercise. I hope that helps!

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Robin Cutler's avatar

One of the best discussions I have read on this topic! And at age 81 I have read a lot of medical articles on cardiovascular issues and multiple other subjects Thank you.

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Helen Reich's avatar

Thank you, you’re the first one to explain inflammatory disease in a way that makes sense. I guess it’s complicated.....

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Nancy Dolan's avatar

Thanks so much for this - really informative.

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Dr. Lucy McBride's avatar

Glad to hear it!

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RLHS's avatar

Do you do high sensitivity CRP and lipoprotein (a) on everyone? My primary just did the standard CBC, CMP and lipid panel. Should I ask for more? Also- do you do hormone levels at a certain age in women - as I believe hormone changes may also play a role from what I’ve been reading?

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Dr. Lucy McBride's avatar

I don’t check a hsCRP and Lp(a) on everyone. I often start checking hs CRP in the 50s … but checking CRP and Lp(a) really depends on age, risk factors, genetics and other factors. I’ve written a bunch about hormone testing and their relative lack of utility .. given that perimenopause and menopause are clinical diagnoses. My interview with Dr. Haver last week shines a light on this. :)

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RLHS's avatar

Thanks!

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Sharon Anderson's avatar

This was very helpful, thank you. My question is, what level of CRP would be suggestive of systematic inflammation and a potential sign of inflamed arteries ?

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Dr. Lucy McBride's avatar

A normal CRP is considered < 3. However a CRP > 3 doesn’t necessarily suggest that your arteries are inflamed. Interpreting a CRP requires a careful and trained physician - especially given that the CRP is a non specific marker of inflammation. I hope that helps!

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Sharon Anderson's avatar

Thank you! Inflammation really seems to be at the base of many chronic health conditions. I’d really like to learn more about effective ways research has shown to reduce this.

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